Fibroblast growth factor‐2/platelet‐derived growth factor enhances atherosclerotic plaque stability
نویسندگان
چکیده
منابع مشابه
Stability Analysis of a Model of Atherosclerotic Plaque Growth
Atherosclerosis, the formation of life-threatening plaques in blood vessels, is a form of cardiovascular disease. In this paper, we analyze a simplified model of plaque growth to derive physically meaningful results about the growth of plaques. In particular, the main results of this paper are two conditions, which express that the immune response increases as LDL cholesterol levels increase an...
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BACKGROUND One of the main challenges in skin flap surgery is tissue ischemia and following necrosis. The present study compares the effects of fibroblast growth factors 1 and 2 on increasing cutaneous vasculature, improving ischemia, and preventing distal necrosis in ischemic skin flaps in rat model. METHODS Thirty rats were allocated into 3 groups (n=10) and 2×8 cm dorsal rando...
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متن کاملGrowth of necrotic cores in atherosclerotic plaque.
Plaques are fatty deposits that grow mainly in arteries and develop as a result of a chronic inflammatory response. Plaques are characterized as 'vulnerable' when they have large internal regions of necrosis and are heavily infiltrated by macrophages. The particular composition of a vulnerable plaque renders it susceptible to rupture, which releases thrombogenic agents into the bloodstream and ...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2019
ISSN: 1582-1838,1582-4934
DOI: 10.1111/jcmm.14850